Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 4/20 | 0.37 |
| ▸ | MGAM | O43451 | 4/20 | 0.37 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | SI | P14410 | 4/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298398 | 1.00 | DGAT1 (0.41) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL29772679 | 0.95 | DGAT1 (0.37) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL8572479 | 0.95 | F12 (0.37) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL5713204 | 0.80 | FAAH (0.36) | MAPT | |
| SCHEMBL4958138 | 0.78 | HDAC3 (0.44) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL5713210 | 0.74 | DGAT1 (0.41) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL6668083 | 0.74 | HDAC3 (0.41) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL29544944 | 0.72 | SIRT2 (0.49) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL118552 | 0.72 | SIRT2 (0.49) | DGAT1SLC9A1POLBMAPK1ATM | |
| SCHEMBL4958146 | 0.72 | SMN1; SMN2 (0.43) | DGAT1SLC9A1POLBMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994118-B2 | Template fixed beta-hairpin loop mimetics and their use in phage display | POLYPHOR LTD. (CH) | 2011-08-09 | — | — | US | disclosed |