Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668090 | 0.95 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL4958670 | 0.81 | FAAH (0.34) | MAPTHPGD | |
| SCHEMBL29544944 | 0.79 | SIRT2 (0.49) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL118552 | 0.79 | SIRT2 (0.49) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL4958138 | 0.78 | HDAC3 (0.44) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| Bromide SCHEMBL5514450 | 0.78 | SIRT2 (0.48) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL5713210 | 0.78 | DGAT1 (0.41) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL15769691 | 0.78 | SIRT2 (0.48) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL30056078 | 0.78 | SIRT2 (0.48) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 | |
| Fluoride Ion SCHEMBL4594160 | 0.78 | SIRT2 (0.48) | SMN1; SMN2NPC1RAB9AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317000-B2 | Glucose-dependent insulins | NOVO NORDISK A/S (DK) | 2008-01-08 | — | — | US | disclosed |