SCHEMBL2298436

SCHEMBL2298436

COc1cc(NC(=O)c2cccc(S(=O)(=O)O)c2)c(OC)cc1N

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
KMT2A Q03164 6/20 0.53
MEN1 O00255 5/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MAPT P10636 4/20 0.50
LMNA P02545 3/20 0.49
HPGD P15428 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPK1 P28482 2/20 0.48
AHR P35869 1/20 0.48
ATM Q13315 1/20 0.47
CYP1A2 P05177 1/20 0.46
USP2 O75604 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2295683 0.91 ALDH1A1 (0.49) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL2294111 0.85 LMNA (0.51) ALDH1A1KMT2ASMN1; SMN2MAPTLMNA
SCHEMBL592866 0.82 MEN1 (0.74) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL29405219 0.82 MEN1 (0.74) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL11785381 0.81 SMN1; SMN2 (0.52) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL394424 0.80 ALDH1A1 (0.50) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL11120074 0.80 MEN1 (0.70) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL11120075 0.80 MEN1 (0.70) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT
SCHEMBL11782589 0.80 ALDH1A1 (0.52) ALDH1A1KMT2ASMN1; SMN2MAPTLMNA
SCHEMBL11598085 0.77 MEN1 (0.69) ALDH1A1KMT2AMEN1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110413-B1 DISPERSING AGENT FOR ORGANIC PIGMENT AND USE THEREOF DAINICHISEIKA COLOR CHEM (JP) 2013-03-20 EP disclosed
US-7993446-B2 Dispersing agent for organic pigment and use thereof DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2011-08-09 US disclosed
US-20100315733-A1 DISPERSING AGENT FOR ORGANIC PIGMENT AND USE THEREOF DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2010-12-16 US disclosed
EP-2110413-A1 DISPERSING AGENT FOR ORGANIC PIGMENT AND USE THEREOF Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2009-10-21 EP disclosed