Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL392265 | 0.87 | SMN1; SMN2 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL4903408 | 0.85 | HSD17B10 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL11785381 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL2298436 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL10049706 | 0.79 | HSD17B10 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL8990107 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27356868 | 0.79 | KDM4E (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11831116 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL31396756 | 0.77 | CYP1A1 (0.67) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10627698 | 0.77 | KMT2A (0.70) | ALDH1A1MEN1KMT2ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101731-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2012-01-24 | — | — | US | disclosed |
| US-8101731-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2012-01-24 | — | — | US | disclosed |
| US-8101731-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION | 2012-01-24 | — | — | US | disclosed |
| US-20100199443-A1 | YELLO ANIONIC DISAZO DYES | LENNARTZ MICHAEL | 2010-08-12 | — | — | US | disclosed |
| US-20100199443-A1 | YELLO ANIONIC DISAZO DYES | LENNARTZ MICHAEL | 2010-08-12 | — | — | US | disclosed |
| US-20100199443-A1 | YELLO ANIONIC DISAZO DYES | LENNARTZ MICHAEL | 2010-08-12 | — | — | US | disclosed |
| US-7723494-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723494-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7723494-B2 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-20080119643-A1 | 4,4'-Diazobenzanilide Dyestuffs | LENNARTZ MICHAEL | 2008-05-22 | — | — | US | disclosed |
| US-20080114158-A1 | Yellow anionic disazo dyes | LENNARTZ MICHAEL | 2008-05-15 | — | — | US | disclosed |
| US-20080114158-A1 | Yellow anionic disazo dyes | LENNARTZ MICHAEL | 2008-05-15 | — | — | US | disclosed |
| US-20080114158-A1 | Yellow anionic disazo dyes | LENNARTZ MICHAEL | 2008-05-15 | — | — | US | disclosed |
| US-7341607-B2 | Based on diaminobenzanilides or, more specifically (aminobenzoylamino),(sulfo-),(methoxy)anilines; stable aqueous solutions;nonbleeding/colorfastness; excellent degrees of exhaustion with high colour strength; dyeing natural or synthetic materials, particularly, paper; neutral or greenish-yellow hues | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-03-11 | — | — | US | disclosed |
| US-7341607-B2 | Based on diaminobenzanilides or, more specifically (aminobenzoylamino),(sulfo-),(methoxy)anilines; stable aqueous solutions;nonbleeding/colorfastness; excellent degrees of exhaustion with high colour strength; dyeing natural or synthetic materials, particularly, paper; neutral or greenish-yellow hues | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-03-11 | — | — | US | disclosed |
| US-20050172420-A1 | Yellow anionic disazo dyes | CIBA SPECIALTY CHEMICALS CORP. | 2005-08-11 | — | — | US | disclosed |
| EP-1509574-A1 | YELLOW ANIONIC DISAZO DYES | Ciba SC Holding AG (CH) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003104333-A1 | YELLOW ANIONIC DISAZO DYES | CIBA SPECIALTY CHEMICALS HOLDING, INC. (CH) | 2003-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119643-A1 | 4,4'-Diazobenzanilide Dyestuffs | CYP4B1, TYR, DDT | ALDH1A1 155/4885MEN1 3273/4885KMT2A 392/4885 |
| US-20050172420-A1 | Yellow anionic disazo dyes | IK, CYB5R3, DCXR | ALDH1A1 3371/4885MEN1 3799/4885KMT2A 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.