Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4406045 | 0.81 | MAPT (0.33) | CYP3A4TDP1MAPTHPGDALDH1A1 | |
| SCHEMBL7262932 | 0.81 | — | — | |
| SCHEMBL507894 | 0.81 | CYP1A2 (0.33) | LMNACYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL7277057 | 0.81 | — | — | |
| SCHEMBL7900149 | 0.81 | — | — | |
| SCHEMBL6671659 | 0.80 | NR1H4 (0.42) | DRD1TYRHPGDTSHRALDH1A1 | |
| SCHEMBL9030835 | 0.80 | CA2 (0.37) | TSHR | |
| SCHEMBL5979923 | 0.80 | PPARG (0.37) | TSHR | |
| SCHEMBL27690945 | 0.79 | ESR1 (0.46) | ESR1ESR2PDCD1CD274LMNA | |
| SCHEMBL8715915 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856278-B2 | Lysophosphatidylserine derivative | THE UNIVERSITY OF TOKYO (JP) | 2018-01-02 | — | — | US | disclosed |
| EP-2258397-B1 | POLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | NIPPON KAYAKU KK (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-20170210767-A1 | LYSOPHOSPHATIDYLSERINE DERIVATIVE | THE UNIVERSITY OF TOKYO (JP) | 2017-07-27 | — | — | US | disclosed |
| US-8946456-B2 | Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol and (R)-feso-deacyl | CHEMI S.P.A. (IT) | 2015-02-03 | — | — | US | disclosed |
| US-8920788-B2 | High-molecular weight conjugate of physiologically active substances | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2014-12-30 | — | — | US | disclosed |
| EP-2580203-B1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | CHEMI SPA (IT) | 2014-08-13 | — | — | EP | disclosed |
| EP-2580203-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | Chemi SPA (IT) | 2013-04-17 | — | — | EP | disclosed |
| US-20130079532-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | CHEMI S.P.A. (IT) | 2013-03-28 | — | — | US | disclosed |
| WO-2011154854-A1 | PROCESS FOR THE PREPARATION OF 2 -HYDROXY- 4 -PHENYL -3, 4 -DIHYDRO-2H-CHROMEN- 6 -YL -METHANOL AND (R) - FESO - DEACYL | CHEMI SPA (IT) | 2011-12-15 | — | — | WO | disclosed |
| US-20110201754-A1 | High-Molecular Weight Conjugate Of Physiologically Active Substances | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2258397-A1 | POLYMER CONJUGATE OF PHYSIOLOGICALLY ACTIVE SUBSTANCE | Nippon Kayaku Kabushiki Kaisha (JP) | 2010-12-08 | — | — | EP | disclosed |
| EP-1362053-B1 | TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME | ENZON INC (US) | 2007-11-14 | — | — | EP | disclosed |
| EP-1362053-A4 | TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME | ENZON INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1362053-A2 | TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME | ENZON, INC. (US) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002065988-A2 | TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME | ENZON, INC. (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201754-A1 | High-Molecular Weight Conjugate Of Physiologically Active Substances | OGFR, ACP1, FCGR2A | ESR1 3088/4885ESR2 2452/4885PDCD1 4698/4885 |
| US-20170210767-A1 | LYSOPHOSPHATIDYLSERINE DERIVATIVE | LPAR3, LPAR1, LPAR4 | ESR1 1789/4885ESR2 2217/4885PDCD1 3942/4885 |
| US-20130079532-A1 | PROCESS FOR THE PREPARATION OF 2-HYDROXY-4-PHENYL-3,4-DIHYDRO-2H-CHROMEN-6-YL-METHANOL AND (R)-FESO-DEACYL | FES, MAOB, BPHL | ESR1 1657/4885ESR2 1485/4885PDCD1 2528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.