SCHEMBL22985648

SCHEMBL22985648

N#Cc1cc(C(F)(F)F)ccc1-c1cccc(-n2c3ccc(C(F)(F)F)cc3c3cc(C(F)(F)F)ccc32)c1-c1c(C#N)cccc1-n1c2ccc(C(F)(F)F)cc2c2cc(C(F)(F)F)ccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
PDK2 Q15119 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SCN9A Q15858 1/20 0.33
HRH1 P35367 1/20 0.32
HTR6 P50406 1/20 0.32
PTGES O14684 1/20 0.32
TEAD1 P28347 2/20 0.32
TEAD4 Q15561 2/20 0.32
TEAD2 Q15562 2/20 0.32
AR P10275 2/20 0.32
CYP3A4 P08684 1/20 0.31
GPBAR1 Q8TDU6 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22985187 0.96 AR (0.33) ALOX5APFEN1PDK2TSHRSMN1; SMN2
SCHEMBL22985640 0.94 MAT2A (0.34) ALOX5APFEN1PDK2TSHRSMN1; SMN2
SCHEMBL22985180 0.93 HTR6 (0.35) ALOX5APFEN1TSHRSMN1; SMN2SCN9A
SCHEMBL22985185 0.92 KIF11 (0.36) ALOX5APFEN1PDK2TSHRSMN1; SMN2
SCHEMBL22985426 0.92 ALOX5AP (0.40) ALOX5APFEN1SMN1; SMN2ARCYP3A4
SCHEMBL22985431 0.91 ALOX5AP (0.36) ALOX5APFEN1TSHRSMN1; SMN2SCN9A
SCHEMBL22985445 0.91 ALOX5AP (0.36) ALOX5APFEN1PDK2SMN1; SMN2AR
SCHEMBL22985319 0.90 KIF11 (0.40) ALOX5APFEN1PDK2PTGESAR
SCHEMBL22985446 0.90 KIF11 (0.33) ALOX5APFEN1PDK2SCN9AHRH1
SCHEMBL22985448 0.90 AR (0.39) ALOX5APFEN1SCN9AARPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices CYNORA GMBH (DE) 2021-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919880-B2 Organic molecules, in particular for use in optoelectronic devices OCIAD1, OCIAD2, POU2F1 ALOX5AP 2567/4885FEN1 2939/4885PDK2 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.