Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8609400 | 0.84 | MEN1 (0.51) | MEN1KMT2ACYP2D6SPHK1GMNN | |
| SCHEMBL7802464 | 0.76 | FAAH (0.49) | MEN1KMT2AGMNNLMNAPOLB | |
| SCHEMBL6487020 | 0.74 | ALDH1A1 (0.61) | MEN1KMT2ASPHK1FFAR4FFAR1 | |
| SCHEMBL20154334 | 0.74 | ALDH1A1 (0.61) | MEN1KMT2ASPHK1FFAR4FFAR1 | |
| SCHEMBL15057401 | 0.73 | SPHK1 (0.55) | MEN1KMT2ACYP2D6SPHK1GMNN | |
| SCHEMBL21636787 | 0.73 | SPHK1 (0.55) | MEN1KMT2ACYP2D6SPHK1GMNN | |
| SCHEMBL21428085 | 0.73 | SPHK1 (0.55) | MEN1KMT2ACYP2D6SPHK1GMNN | |
| SCHEMBL7800250 | 0.73 | CYP2D6 (0.47) | MEN1KMT2ACYP2D6SPHK1GMNN | |
| SCHEMBL7802392 | 0.73 | CYP2D6 (0.47) | MEN1KMT2ACYP2D6SPHK1GMNN | |
| Hydrochloric Acid SCHEMBL7612591 | 0.72 | SPHK1 (0.53) | MEN1KMT2ACYP2D6SPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777891-A1 | ARTIFICIALLY SYNTHESIZED SPHINGOSINE DERIVATIVE LIPOID MONOMER AND USE OF SAME FOR DELIVERING NUCLEIC ACID | Institute of Basic Medical Sciences, Chinese Academi of Medical Sciences (CN) | 2021-02-17 | — | — | EP | disclosed |