Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800250 | 1.00 | CYP2D6 (0.47) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL7802415 | 0.92 | FAAH (0.44) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL7802466 | 0.92 | FAAH (0.44) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL7800236 | 0.81 | CYP2D6 (0.41) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL1221410 | 0.79 | GPR84 (0.42) | MAPTGPR84FFAR1 | |
| SCHEMBL8389902 | 0.75 | EPHX1 (0.42) | SPHK1MAPTMEN1KMT2AGPR84 | |
| SCHEMBL15057401 | 0.73 | SPHK1 (0.55) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL21636787 | 0.73 | SPHK1 (0.55) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL21428085 | 0.73 | SPHK1 (0.55) | CYP2D6SPHK1LMNAGMNNPOLB | |
| SCHEMBL22986826 | 0.73 | MEN1 (0.49) | CYP2D6SPHK1LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915081-B1 | Ceramide compounds, process for their preparation and use | OREAL (FR) | 2001-08-22 | — | — | EP | claimed |
| US-6077972-A | PREPARATION BY REACTING AN AMINODIOL WITH AN AZOLIDE DERIVATIVE IN AN INERT SOLVENT TO OBTAIN THE DESIRED COMPOUND. COSMETICS | L'OREAL (FR) | 2000-06-20 | — | — | US | claimed |
| US-6203808-B1 | APPLYING AQUEOUS DISPERSION OF LIPID SPHERES COMPRISING HYDROXYALKYLUREA DERIVATIVES; AGING RESISTANCE COSMETICS FOR HAIR, SKIN, NAILS, EYEBROWS AND LASHES | L'OREAL (FR) | 2001-03-20 | — | — | US | disclosed |
| US-6077972-A | PREPARATION BY REACTING AN AMINODIOL WITH AN AZOLIDE DERIVATIVE IN AN INERT SOLVENT TO OBTAIN THE DESIRED COMPOUND. COSMETICS | L'OREAL (FR) | 2000-06-20 | — | — | US | disclosed |