Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430826 | 0.83 | CASP2 (0.47) | FAAHL3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL23986767 | 0.82 | RECQL (0.56) | L3MBTL1GAARECQLALDH1A1TSHR | |
| SCHEMBL17570975 | 0.80 | RECQL (0.37) | FAAHGAARECQLALDH1A1KMT2A | |
| SCHEMBL17570983 | 0.77 | RECQL (0.39) | GAARECQL | |
| SCHEMBL16472228 | 0.77 | EPHX2 (0.35) | KMT2ATSHR | |
| SCHEMBL16710720 | 0.76 | FAAH (0.53) | FAAH | |
| SCHEMBL9483993 | 0.76 | FAAH (0.50) | FAAHMCL1L3MBTL1GAARECQL | |
| SCHEMBL16472227 | 0.75 | LMNA (0.33) | RECQLALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL21012621 | 0.75 | TSHR (0.48) | GAARECQLALDH1A1KMT2ATSHR | |
| SCHEMBL19456828 | 0.75 | TDP1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |