Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12347932 | 1.00 | LMNA (0.51) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL22987362 | 0.88 | LMNA (0.53) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL2059341 | 0.88 | LMNA (0.56) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL2438788 | 0.87 | LMNA (0.52) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL22122416 | 0.86 | LMNA (0.57) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL22122414 | 0.86 | LMNA (0.57) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL851947 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL851946 | 0.84 | LMNA (0.52) | LMNASMN1; SMN2SYKMAPTHTT | |
| SCHEMBL20046452 | 0.84 | CA2 (0.58) | SYKMAPTCA2CA5ACTSL | |
| SCHEMBL20075956 | 0.84 | CA2 (0.58) | SYKMAPTCA2CA5ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | disclosed |