Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | REN | P00797 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616958 | 0.85 | RECQL (0.39) | RECQLTSHRBIRC2HRH3NPSR1 | |
| SCHEMBL17570956 | 0.85 | RECQL (0.39) | RECQLTSHRBIRC2HRH3NPSR1 | |
| SCHEMBL22064160 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNARECQLTSHRKMT2A | |
| SCHEMBL19656347 | 0.81 | PSENEN (0.40) | RECQLTSHRBIRC2REN | |
| SCHEMBL25908085 | 0.81 | PSENEN (0.40) | RECQLTSHRBIRC2REN | |
| SCHEMBL22064571 | 0.80 | RECQL (0.48) | ALDH1A1LMNARECQLTSHRCAPN1 | |
| SCHEMBL18914007 | 0.77 | RECQL (0.39) | ALDH1A1LMNARECQLTSHRHRH3 | |
| SCHEMBL22987361 | 0.77 | RECQL (0.39) | ALDH1A1LMNARECQLTSHRHRH3 | |
| SCHEMBL22987342 | 0.76 | RECQL (0.53) | ALDH1A1LMNARECQLTSHRHRH3 | |
| SCHEMBL25122213 | 0.76 | RECQL (0.53) | ALDH1A1LMNARECQLTSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313884-B9 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | IMMUNOGEN INC (US) | 2021-05-19 | — | — | EP | disclosed |
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |