SCHEMBL22989063

SCHEMBL22989063

c1ccc(-c2ccc(-c3nc4ccccc4nc3-c3ccc4cc(-n5c6ccc7cccc8sc9cccc%10ccc5c(c%109)c6c78)ccc4c3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
THRB P10828 1/20 0.36
PDE10A Q9Y233 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
AKT1 P31749 1/20 0.34
AKT2 P31751 1/20 0.34
HPGD P15428 2/20 0.34
MAPK9 P45984 1/20 0.33
MAPK10 P53779 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989059 0.99 LMNA (0.39) LMNAL3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL22989067 0.96 L3MBTL1 (0.38) LMNAL3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL22989065 0.94 MAPK10 (0.38) LMNAL3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL22989058 0.89 HPGD (0.33) PDE10AHPGDMAPK9MAPK10
SCHEMBL22989066 0.88 FLT3 (0.33) LMNAALDH1A1KDM4EPDE10AHPGD
SCHEMBL22989182 0.87 MEN1 (0.40) LMNAKDM4EADORA2AMEN1KMT2A
SCHEMBL22989259 0.86 KDM4E (0.36) LMNAL3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL22989223 0.86 L3MBTL1 (0.41) LMNAL3MBTL1ALDH1A1KDM4ETDP1
SCHEMBL22989184 0.85 MEN1 (0.41) LMNAKDM4EADORA2AMEN1KMT2A
SCHEMBL22989094 0.85 AKT1 (0.38) LMNAL3MBTL1ALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed