SCHEMBL22989065

SCHEMBL22989065

c1ccc2cc(-c3nc4ccccc4nc3-c3ccc4cc(-n5c6ccc7cccc8sc9cccc%10ccc5c(c%109)c6c78)ccc4c3)ccc2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 7/20 0.38
MAPK9 P45984 6/20 0.38
PDE10A Q9Y233 1/20 0.35
HPGD P15428 1/20 0.34
MAPK8 P45983 2/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
POLB P06746 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GRM1 Q13255 1/20 0.32
PMM2 O15305 1/20 0.32
MPI P34949 1/20 0.32
PHOSPHO1 Q8TCT1 1/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989059 0.95 LMNA (0.39) MAPK10MAPK9PDE10AHPGDMAPT
SCHEMBL22989067 0.94 L3MBTL1 (0.38) MAPK10MAPK9PDE10AHPGDMAPK8
SCHEMBL22989063 0.94 LMNA (0.39) MAPK10MAPK9PDE10AHPGDMAPT
SCHEMBL22989058 0.92 HPGD (0.33) MAPK10MAPK9PDE10AHPGDPMM2
SCHEMBL22989066 0.91 FLT3 (0.33) MAPK10MAPK9PDE10AHPGDMAPT
SCHEMBL22989062 0.87 HPGD (0.33) HPGDMAPTPOLBKDM4EALDH1A1
SCHEMBL22989263 0.87 PDE10A (0.35) MAPK10MAPK9PDE10AMAPK8MAPT
SCHEMBL22989094 0.86 AKT1 (0.38) MAPK10MAPK9PDE10AHPGDL3MBTL1
SCHEMBL22989193 0.86 HPGD (0.36) MAPK10MAPK9HPGDMAPTADORA2A
SCHEMBL22989218 0.85 L3MBTL1 (0.36) MAPK10MAPK9PDE10AHPGDMAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed