SCHEMBL22989260

SCHEMBL22989260

Clc1ccccc1-c1nc2ccccc2nc1-c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.63
L3MBTL1 Q9Y468 5/20 0.63
LMNA P02545 4/20 0.63
GAA P10253 2/20 0.63
PKM P14618 1/20 0.60
ALDH1A1 P00352 5/20 0.57
CYP2A6 P11509 1/20 0.54
KMT2A Q03164 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
MEN1 O00255 1/20 0.53
GLA P06280 1/20 0.53
AKT1 P31749 1/20 0.50
AKT2 P31751 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
ATM Q13315 1/20 0.46
TLR9 Q9NR96 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989180 0.86 KDM4E (0.56) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL732131 0.81 KDM4E (0.74) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL29382173 0.81 KDM4E (0.74) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL18239215 0.80 KDM4E (0.59) KDM4EL3MBTL1LMNAGAAPKM
Water SCHEMBL27680271 0.79 KDM4E (0.71) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL28710728 0.79 KDM4E (0.71) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL13950894 0.79 KDM4E (0.78) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL865711 0.79 KDM4E (0.71) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL24589920 0.78 L3MBTL1 (0.63) KDM4EL3MBTL1LMNAGAAPKM
SCHEMBL24689392 0.78 KDM4E (0.64) KDM4EL3MBTL1LMNAGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed