Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.77 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22260878 | 0.88 | PLK1 (0.65) | PLK1EGLN1MEN1KMT2ARIPK1 | |
| SCHEMBL11962154 | 0.87 | PLK1 (1.00) | PLK1MEN1KMT2ARIPK1ALOX15 | |
| SCHEMBL3362629 | 0.85 | HDAC6 (0.65) | PLK1EGLN1MEN1KMT2ACHRNA7 | |
| SCHEMBL13740774 | 0.83 | RIPK1 (0.57) | PLK1EGLN1MEN1KMT2ARIPK1 | |
| Hydrochloric Acid SCHEMBL13739996 | 0.82 | RIPK1 (0.56) | PLK1EGLN1MEN1KMT2ARIPK1 | |
| SCHEMBL9360254 | 0.81 | MEN1 (0.55) | PLK1EGLN1MEN1KMT2ACHRNA7 | |
| SCHEMBL29977567 | 0.81 | MEN1 (0.55) | PLK1EGLN1MEN1KMT2ACHRNA7 | |
| SCHEMBL17941874 | 0.81 | EGLN1 (0.62) | PLK1EGLN1MEN1KMT2ARIPK1 | |
| SCHEMBL29893321 | 0.81 | ALOX15 (0.77) | PLK1EGLN1MEN1KMT2ACHRNA7 | |
| SCHEMBL2671065 | 0.81 | ALOX15 (0.77) | PLK1EGLN1MEN1KMT2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-2519505-A1 | NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | Polichem SA (LU) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011080264-A1 | NEW TERTIARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES AND USES THEREOF | POLICHEM S.A. (LU) | 2011-07-07 | — | — | WO | disclosed |