Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 3/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106775 | 0.83 | PRMT5 (0.40) | ALDH1A1 | |
| SCHEMBL27252311 | 0.82 | ALDH1A1 (0.55) | LMNATYMPKDM4EALDH1A1ALB | |
| SCHEMBL9548812 | 0.82 | ALDH1A1 (0.55) | LMNATYMPKDM4EALDH1A1ALB | |
| SCHEMBL20224942 | 0.81 | LMNA (0.60) | LMNASMN1; SMN2TYMPALOX12ADRA1A | |
| SCHEMBL26273448 | 0.81 | LMNA (0.63) | LMNASMN1; SMN2RNASE1ALOX12ADRA1A | |
| SCHEMBL9318488 | 0.81 | LMNA (0.63) | LMNASMN1; SMN2RNASE1ALOX12ADRA1A | |
| SCHEMBL25372583 | 0.81 | LMNA (0.63) | LMNASMN1; SMN2RNASE1ALOX12ADRA1A | |
| SCHEMBL9318484 | 0.81 | LMNA (0.63) | LMNASMN1; SMN2RNASE1ALOX12ADRA1A | |
| SCHEMBL25679985 | 0.80 | ADK (0.35) | LMNASMN1; SMN2TYMPALDH1A1ALB | |
| SCHEMBL21073950 | 0.77 | ADK (0.34) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-B1 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-02-17 | — | — | EP | disclosed |