SCHEMBL22990780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4382049	1.00	POLQ (0.49)	POLQF10GFERPTGDR2NPSR1
	SCHEMBL4385663	0.90	F10 (0.50)	F10GFERPTGDR2NPSR1KMT2A
	SCHEMBL4386402	0.82	GFER (0.58)	GFERNPSR1KMT2AMEN1SMN1; SMN2
	SCHEMBL4393341	0.80	POLB (0.52)	GFERNPSR1KMT2AMEN1GAA
	SCHEMBL4391109	0.79	POLB (0.55)	POLQF10GFERPTGDR2NPSR1
	SCHEMBL22990713	0.78	F10 (0.39)	F10PTGDR2NPC1RAB9ASMN1; SMN2
	SCHEMBL29658932	0.78	F10 (0.39)	F10PTGDR2NPC1RAB9ASMN1; SMN2
	SCHEMBL15743850	0.78	SMN1; SMN2 (0.48)	PTGDR2NPC1RAB9ASMN1; SMN2
	SCHEMBL8290690	0.78	SMN1; SMN2 (0.48)	PTGDR2NPC1RAB9ASMN1; SMN2
	SCHEMBL3600152	0.78	SMN1; SMN2 (0.53)	NPSR1KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.