Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845188 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL3600148 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL11253251 | 0.91 | ALDH1A1 (0.52) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL8290690 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL15743850 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL10756834 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL11764943 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL1331012 | 0.88 | TSHR (0.52) | SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL29816738 | 0.87 | KMT2A (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C | |
| SCHEMBL20886535 | 0.87 | KMT2A (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321606-A | Preparation method of (S) -1- (benzyloxycarbonyl) -5-oxopyrrolidine-2-formic acid | 吉尔生化（上海）有限公司 | 2021-08-31 | — | — | CN | claimed |
| EP-0187052-B1 | ADAMANTAN AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | S.A. PANMEDICA Société dite: (FR) | 1990-01-31 | — | — | EP | claimed |
| EP-0085283-A1 | Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications | Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) | 1983-08-10 | — | — | EP | claimed |
| US-12103928-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2024-10-01 | — | — | US | disclosed |
| CN-114516898-B | Preparation method and application of thyrotropin releasing hormone | 上海丽珠制药有限公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-10-19 | — | — | US | disclosed |
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2023-08-22 | — | — | US | disclosed |
| CN-115073458-A | Preparation method of avibactam sodium | 山东致泰医药技术有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114667167-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114516898-A | Preparation method and application of thyrotropin releasing hormone | 上海丽珠制药有限公司 | 2022-05-20 | — | — | CN | disclosed |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2021-12-02 | — | — | US | disclosed |
| US-4923984-A | TREATMENT OF SENILE DEMENTIA, PSYCHONEUROSIS, AMNESIA | SHIONOGI & CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0353778-A2 | Pyrrolo[1,4]benzodiazepine derivatives | SHIONOGI & CO., LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |
| US-4883869-A | BACTERICIDES, ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0187500-A1 | Monobactams | THE UPJOHN COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0106282-A2 | Production of caerulein intermediate | Shionogi & Co., Ltd. (JP) | 1984-04-25 | — | — | EP | disclosed |
| EP-0085283-A1 | Pyroglutamyl-tryptophan derivatives, process for their preparation and their therapeutic applications | Società Italo-Britannica L. Manetti - H. Roberts & C. (IT) | 1983-08-10 | — | — | EP | disclosed |
| US-4305872-A | HYPOTHALAMIC RELEASING AND INHIBITORY FACTORS, ENKEPHALINS AND ANTAGONISTS TO PRECURSOR PEPTIDES USEFUL IN BIOASSAY | Wingrove, Kenneth (US) | 1981-12-15 | — | — | US | disclosed |
| US-3974135-A | Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for producing the same | FOLKERS KARL | 1976-08-10 | — | — | US | disclosed |
| US-3966700-A | Process for preparing synthetic L-pyroglutamyl-L-histidyl-L-prolinamide | ISTITUTO FARMACOLOGICO SERONO, S.P.A. (IT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731971-B2 | Processes for preparing a diazabicyclooctane compound | FN1, BMP1, AZI2 | SMN1; SMN2 702/4885NPC1 903/4885RAB9A 816/4885 |
| US-20210371419-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | FN1, BMP1, AZI2 | SMN1; SMN2 702/4885NPC1 903/4885RAB9A 816/4885 |
| US-20230331724-A1 | PROCESSES FOR PREPARING A DIAZABICYCLOOCTANE COMPOUND | FN1, BMP1, AZI2 | SMN1; SMN2 702/4885NPC1 903/4885RAB9A 816/4885 |
| US-12103928-B2 | Processes for preparing a diazabicyclooctane compound | FN1, BMP1, AZI2 | SMN1; SMN2 702/4885NPC1 903/4885RAB9A 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.