Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344266 | 0.91 | TSHR (0.37) | NAMPTCYP11B1CYP11B2CYP46A1CYP2D6 | |
| SCHEMBL21344849 | 0.91 | TSHR (0.37) | NAMPTCYP11B1CYP11B2CYP2D6CYP2C9 | |
| SCHEMBL22992144 | 0.90 | CYP11B1 (0.37) | NAMPTCYP11B1CYP11B2CYP46A1CYP2D6 | |
| SCHEMBL22992155 | 0.89 | CYP3A4 (0.44) | USP2CYP2D6CYP2C9TSHRHSD17B10 | |
| SCHEMBL24426554 | 0.87 | ALDH1A1 (0.43) | CYP2C9 | |
| SCHEMBL21344669 | 0.86 | CHRM2 (0.45) | NAMPTTDP1 | |
| SCHEMBL22992040 | 0.85 | CYP3A4 (0.47) | USP2CYP2D6CYP2C9TSHRHSD17B10 | |
| SCHEMBL22992214 | 0.84 | CCR8 (0.42) | NAMPTUSP2CYP2D6CYP2C9TSHR | |
| SCHEMBL22992057 | 0.84 | ACACA (0.38) | NAMPTUSP2CYP2D6CYP2C9TSHR | |
| SCHEMBL21344672 | 0.84 | VNN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | NAMPT 3453/4885CYP11B1 591/4885CYP11B2 866/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | NAMPT 3453/4885CYP11B1 591/4885CYP11B2 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.