SCHEMBL5710067

SCHEMBL5710067

Cc1cn([C@H]2C[C@H](OC(=O)c3ccc(Cl)cc3)[C@@H](COC(=O)c3ccc(Cl)cc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.68
UPP1 Q16831 1/20 0.54
TK1 P04183 4/20 0.49
TK2 O00142 2/20 0.49
ABCG2 Q9UNQ0 3/20 0.48
ABCB1 P08183 1/20 0.48
TERT O14746 2/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA5A P35218 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA5B Q9Y2D0 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9326675 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL10664373 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL9324478 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL21886791 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL30976654 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL22992340 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL13273339 0.91 RNASE1 (0.82) RNASE1TK1TK2ABCG2ABCB1
SCHEMBL7071383 0.90 RNASE1 (0.55) RNASE1UPP1TK1TK2
SCHEMBL6237573 0.90 RNASE1 (0.55) RNASE1UPP1TK1TK2
SCHEMBL20833584 0.89 UPP1 (0.54) RNASE1UPP1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1186612-B1 PROCESS FOR THE PREPARATION OF CYTIDINE DERIVATIVES MITSUI CHEMICALS INC (JP) 2006-11-29 EP disclosed
US-6822090-B2 GENERATION OF PREFERENTIAL URIDINE DERIVATIVE; OBTAIN REACTION MIXTURE, EXPOSE TO TERTIARY AMINE, DEHYDRATING REACTANT AND AMMONIA, RECOVER CYTIDINE DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2004-11-23 US disclosed
US-20030032797-A1 Process for the preparation of cytidine derivatives MITSUI CHEMICALS, INC. (JP) 2003-02-13 US disclosed
EP-1186612-A1 PROCESS FOR THE PREPARATION OF CYTIDINE DERIVATIVES Mitsui Chemicals, Inc. (JP) 2002-03-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030032797-A1 Process for the preparation of cytidine derivatives CDA, DCTD, APOBEC3A RNASE1 465/4885UPP1 68/4885TK1 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.