Sugi Predict

Sugi Predict / Compounds / SCHEMBL7875892

SCHEMBL7875892

SCHEMBL7875892

Cc1cn([C@@H]2C[C@@H](OC(=O)c3ccccc3)[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ RNASE1 P07998 1/20 1.00
▸ TK1 P04183 4/20 0.56
▸ TK2 O00142 3/20 0.56
▸ POLB P06746 1/20 0.55
▸ ALB P02768 1/20 0.54
▸ PKM P14618 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ BLM P54132 1/20 0.54
▸ PMP22 Q01453 1/20 0.54
▸ TSHR P16473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992433 1.00 RNASE1 (1.00) RNASE1TK1TK2POLBALB
SCHEMBL3279568 1.00 RNASE1 (1.00) RNASE1TK1TK2POLBALB
SCHEMBL2056750 1.00 RNASE1 (1.00) RNASE1TK1TK2POLBALB
SCHEMBL7875887 1.00 RNASE1 (1.00) RNASE1TK1TK2POLBALB
Barbituric Acid SCHEMBL9710100 0.93 RNASE1 (0.86) RNASE1TK1TK2POLB
SCHEMBL9326675 0.90 RNASE1 (0.82) RNASE1TK1TK2
SCHEMBL13273339 0.90 RNASE1 (0.82) RNASE1TK1TK2
SCHEMBL21886791 0.90 RNASE1 (0.82) RNASE1TK1TK2
SCHEMBL22992340 0.90 RNASE1 (0.82) RNASE1TK1TK2
SCHEMBL30976654 0.90 RNASE1 (0.82) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329346-B1 POLYNUCLEOTIDES WITH CARRIERS ROCHE DIAGNOSTICS GMBH (DE) 2001-12-11 — — US disclosed
EP-0611373-B1 OLIGO-2'-DEOXYNUCLEOTIDES AND THEIR USE AS DRUGS WITH AN ANTIVIRAL ACTION BOEHRINGER MANNHEIM GMBH (DE) 1997-03-26 — — EP disclosed