Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.60 |
| ▸ | TK1 | P04183 | 5/20 | 0.54 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962393 | 1.00 | DHFR (0.60) | DHFRTK1NT5MALBPKM | |
| SCHEMBL2511666 | 0.85 | DHFR (0.67) | DHFRTK1NT5MALBPKM | |
| SCHEMBL31084252 | 0.85 | DHFR (0.67) | DHFRTK1NT5MALBPKM | |
| SCHEMBL2455603 | 0.85 | DHFR (0.67) | DHFRTK1NT5MALBPKM | |
| SCHEMBL12303789 | 0.85 | DHFR (0.67) | DHFRTK1NT5MALBPKM | |
| SCHEMBL9216396 | 0.80 | NT5M (0.59) | DHFRTK1NT5M | |
| SCHEMBL13847480 | 0.80 | NT5M (0.59) | DHFRTK1NT5M | |
| SCHEMBL5953204 | 0.76 | DHFR (0.36) | DHFRTK1NT5MALB | |
| SCHEMBL17117066 | 0.76 | TK1 (0.56) | DHFRTK1LMNABLMPMP22 | |
| SCHEMBL14590480 | 0.75 | TK1 (0.59) | DHFRTK1ALBPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |