Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 10/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 10/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22993180 | 0.88 | F11 (0.61) | F11KLKB1 | |
| SCHEMBL22993477 | 0.87 | F11 (0.70) | F11KLKB1 | |
| SCHEMBL29390911 | 0.83 | F11 (0.80) | F11KLKB1 | |
| SCHEMBL22993499 | 0.82 | F11 (0.56) | F11KLKB1 | |
| SCHEMBL22993383 | 0.80 | F11 (0.69) | F11KLKB1 | |
| SCHEMBL22993482 | 0.78 | KLKB1 (0.73) | F11KLKB1 | |
| SCHEMBL22993231 | 0.77 | F11 (0.40) | F11KLKB1 | |
| SCHEMBL22993238 | 0.76 | HDAC1 (0.46) | F11KLKB1 | |
| SCHEMBL29405895 | 0.75 | HDAC1 (0.45) | F11KLKB1 | |
| SCHEMBL29407285 | 0.72 | F11 (0.87) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028645-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |
| WO-2021028649-A1 | PLASMA KALLIKREIN INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-02-18 | — | — | WO | disclosed |