SCHEMBL22993153

SCHEMBL22993153

Cc1cc2c(-c3ccc(C(F)(F)F)cc3)c3ccccc3c(-c3cccc4ccccc34)c2cc1C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
TP53 P04637 2/20 0.39
TNKS O95271 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
PARP2 Q9UGN5 1/20 0.39
ENPP1 P22413 3/20 0.39
KIF11 P52732 1/20 0.38
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
ESR1 P03372 2/20 0.37
KCNQ3 O43525 2/20 0.37
KCNQ2 O43526 2/20 0.37
DHFR P00374 1/20 0.37
BACE1 P56817 1/20 0.36
PSD A5PKW4 1/20 0.36
HSD11B1 P28845 1/20 0.36
ENPP3 O14638 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993255 0.92 CA12 (0.41) MAPTTP53TNKSTNKS2PARP2
SCHEMBL22978409 0.90 KIF11 (0.46) TNKSTNKS2ENPP1KIF11CA12
SCHEMBL13298650 0.89 KIF11 (0.48) TNKSTNKS2ENPP1KIF11CA12
SCHEMBL22993156 0.88 CYP1A1 (0.42) ENPP1ESR1
SCHEMBL22993538 0.88 CYP11B1 (0.39) TNKSTNKS2ENPP1KIF11ESR1
SCHEMBL22993331 0.87 ENPP1 (0.43) ENPP1KIF11CA12CA1CA2
SCHEMBL22993259 0.86 CYP1A1 (0.43) CA12CA1CA2CA9PSD
SCHEMBL13298640 0.85 HDAC8 (0.40) ENPP1KIF11CA12CA1CA2
SCHEMBL13298635 0.85 HDAC8 (0.40) ENPP1KIF11CA12CA1CA2
SCHEMBL13298643 0.85 HDAC8 (0.40) ENPP1KIF11CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed