SCHEMBL22993259

SCHEMBL22993259

Cc1cc2c(-c3cccc4ccccc34)c3ccc(-c4cccc(C(F)(F)F)c4)cc3c(-c3cccc4ccccc34)c2cc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP1B1 Q16678 1/20 0.43
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
PDPK1 O15530 1/20 0.37
IKBKB O14920 1/20 0.37
PGR P06401 1/20 0.37
BRD4 O60885 1/20 0.37
MAPK14 Q16539 1/20 0.37
PSD A5PKW4 1/20 0.37
MAOB P27338 2/20 0.36
CNR2 P34972 1/20 0.36
PARP1 P09874 1/20 0.36
PTPN5 P54829 1/20 0.36
KDM1A O60341 1/20 0.36
MCL1 Q07820 1/20 0.36
BAD Q92934 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993301 0.94 CYP1A1 (0.47) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993156 0.92 CYP1A1 (0.42) CYP1A1CYP1A2CYP1B1IKBKBBRD4
SCHEMBL22993085 0.91 PTPN5 (0.46) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993255 0.91 CA12 (0.41) CA12CA1CA2CA9PSD
SCHEMBL22992996 0.91 CYP1A1 (0.45) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993318 0.90 ENPP1 (0.43) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993548 0.90 CYP1A1 (0.44) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993317 0.89 PTPN5 (0.44) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993532 0.88 PGR (0.43) CYP1A1CYP1A2CYP1B1CA12CA1
SCHEMBL22993153 0.86 MAPT (0.39) CA12CA1CA2CA9PSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed