SCHEMBL22993494

SCHEMBL22993494

CC(C)(C)c1ccc(-c2ccc3c(-c4cc5ccccc5c5ccccc45)c4cc(-c5ccc(OC(F)(F)F)cc5)cc(-c5cc6ccccc6c6ccccc56)c4cc3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.39
SERPINE1 P05121 1/20 0.37
TRPV1 Q8NER1 2/20 0.36
ACP1 P24666 1/20 0.34
PPARG P37231 2/20 0.34
PPARA Q07869 2/20 0.34
EPHX2 P34913 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
CYP11B1 P15538 3/20 0.33
CYP11B2 P19099 3/20 0.33
AURKA O14965 1/20 0.31
TPX2 Q9ULW0 1/20 0.31
KIF11 P52732 1/20 0.31
SCN5A Q14524 1/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993138 1.00 GPR84 (0.39) GPR84SERPINE1TRPV1ACP1PPARG
SCHEMBL22993143 0.93 CYP11B1 (0.36) GPR84SERPINE1ACP1CYP11B1CYP11B2
SCHEMBL22993079 0.92 CYP11B1 (0.34) SERPINE1ACP1CYP11B1CYP11B2AURKA
SCHEMBL22993528 0.92 CYP11B1 (0.34) SERPINE1ACP1CYP11B1CYP11B2AURKA
SCHEMBL22993516 0.91 TRPV1 (0.41) GPR84SERPINE1TRPV1ACP1PPARG
SCHEMBL22993496 0.90 ACP1 (0.35) GPR84SERPINE1ACP1CYP11B1CYP11B2
SCHEMBL22993530 0.90 ACP1 (0.35) GPR84SERPINE1ACP1CYP11B1CYP11B2
SCHEMBL22993525 0.89 GPR84 (0.35) GPR84SERPINE1ACP1CYP11B1CYP11B2
SCHEMBL22992953 0.89 GPR84 (0.35) GPR84SERPINE1ACP1CYP11B1CYP11B2
SCHEMBL22993536 0.89 GPR84 (0.42) GPR84TRPV1CYP11B1CYP11B2KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed