SCHEMBL22993530

SCHEMBL22993530

Cc1ccc(-c2cc(-c3cc4ccccc4c4ccccc34)c3cc4cc(-c5ccc(OC(F)(F)F)cc5)ccc4c(-c4cc5ccccc5c5ccccc45)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 1/20 0.35
GPR84 Q9NQS5 2/20 0.35
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
MMP12 P39900 1/20 0.34
AURKA O14965 1/20 0.32
TPX2 Q9ULW0 1/20 0.32
KIF11 P52732 1/20 0.32
SCN5A Q14524 1/20 0.32
GPR3 P46089 1/20 0.32
TP53 P04637 1/20 0.32
ALOX5 P09917 1/20 0.31
SERPINE1 P05121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993496 1.00 ACP1 (0.35) ACP1GPR84CYP11B1CYP11B2MMP12
SCHEMBL22993143 0.95 CYP11B1 (0.36) ACP1GPR84CYP11B1CYP11B2AURKA
SCHEMBL22993525 0.91 GPR84 (0.35) ACP1GPR84CYP11B1CYP11B2AURKA
SCHEMBL22992953 0.91 GPR84 (0.35) ACP1GPR84CYP11B1CYP11B2AURKA
SCHEMBL22993272 0.90 ACP1 (0.40) ACP1GPR84CYP11B1CYP11B2MMP12
SCHEMBL22993494 0.90 GPR84 (0.39) ACP1GPR84CYP11B1CYP11B2AURKA
SCHEMBL22993138 0.90 GPR84 (0.39) ACP1GPR84CYP11B1CYP11B2AURKA
SCHEMBL22993079 0.90 CYP11B1 (0.34) ACP1CYP11B1CYP11B2AURKATPX2
SCHEMBL22993528 0.90 CYP11B1 (0.34) ACP1CYP11B1CYP11B2AURKATPX2
SCHEMBL26803588 0.89 KIF11 (0.34) ACP1CYP11B1CYP11B2AURKATPX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed