SCHEMBL2299446

SCHEMBL2299446

CCCCCC(CC(O)CO)(CC(O)CO)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
DUSP3 P51452 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.41
GPR84 Q9NQS5 7/20 0.39
FFAR1 O14842 2/20 0.38
FFAR4 Q5NUL3 1/20 0.38
USP2 O75604 1/20 0.38
ACACB O00763 1/20 0.38
ACACA Q13085 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2223196 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL4611332 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL290355 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2745700 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL1162330 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL3335410 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL525690 0.98 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL2193108 0.95 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL29118739 0.95 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL27837711 0.95 KDM4E (0.44) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9320693-B2 Cosmetic composition with a volumizing effect L'OREAL (FR) 2016-04-26 US claimed
EP-1800650-B2 Cosmetic composition providing a voluminous effect OREAL (FR) 2013-08-14 EP claimed
EP-1800649-B2 Cosmetic composition with volumising effect OREAL (FR) 2012-10-10 EP claimed
WO-2011101239-A2 COSMETIC OR DERMATOLOGICAL USES OF A POWDER COMPRISING A FILLER, AN ESSENTIAL OIL AND A HYDROXYLATED ESTER OF POLYOL AND OF C4 TO C16 CARBOXYLIC ACID(S) L'OREAL (FR) 2011-08-25 WO claimed
EP-1800650-B1 Cosmetic composition providing a voluminous effect OREAL (FR) 2010-11-03 EP claimed
EP-1800649-B1 Cosmetic composition with volumising effect OREAL (FR) 2008-12-10 EP claimed
US-20070141003-A1 Cosmetic composition with a volumizing effect L'OREAL (FR) 2007-06-21 US claimed
CN-114007573-B Cosmetic composition in the form of an oil-in-water emulsion 莱雅公司 2024-12-24 CN disclosed
US-20210121379-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'OREAL (FR) 2021-04-29 US disclosed
EP-3532022-B1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS OREAL (FR) 2020-11-25 EP disclosed
EP-3532022-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'Oreal (FR) 2019-09-04 EP disclosed
US-20190240123-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'OREAL (FR) 2019-08-08 US disclosed
US-20180360713-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'OREAL (FR) 2018-12-20 US disclosed
WO-2018078095-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'OREAL (FR) 2018-05-03 WO disclosed
WO-2017103240-A9 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'OREAL (FR) 2018-04-26 WO disclosed
WO-2017103240-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS L'OREAL (FR) 2017-06-22 WO disclosed
US-9320693-B2 Cosmetic composition with a volumizing effect L'OREAL (FR) 2016-04-26 US disclosed
WO-2012059343-A1 COMPOSITION IN THE POWDER FORM COMPRISING AT LEAST ONE ESSENTIAL OIL AND ONE MODIFIED TAPIOCA STARCH L'OREAL (FR) 2012-05-10 WO disclosed
WO-2011101239-A2 COSMETIC OR DERMATOLOGICAL USES OF A POWDER COMPRISING A FILLER, AN ESSENTIAL OIL AND A HYDROXYLATED ESTER OF POLYOL AND OF C4 TO C16 CARBOXYLIC ACID(S) L'OREAL (FR) 2011-08-25 WO disclosed
US-20070141003-A1 Cosmetic composition with a volumizing effect L'OREAL (FR) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141003-A1 Cosmetic composition with a volumizing effect CUTA, ELOVL1, LIPA KDM4E 2977/4885DUSP3 4778/4885MEN1 492/4885
US-20190240123-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS KRT18, CUTA, MGLL KDM4E 3611/4885DUSP3 3398/4885MEN1 3878/4885
US-20180360713-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS MGLL, GK, LIPA KDM4E 1627/4885DUSP3 1977/4885MEN1 4470/4885
US-20210121379-A1 COMPOSITION COMPRISING AT LEAST TWO FATTY ACID ESTERS OF (POLY)GLYCEROL, AND USE THEREOF IN COSMETICS MGLL, GK, LIPA KDM4E 1634/4885DUSP3 1976/4885MEN1 4445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.