Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604312 | 0.87 | KDR (0.64) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL11407984 | 0.87 | ALDH1A1 (0.70) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL974386 | 0.86 | ALDH1A1 (0.71) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL7970930 | 0.84 | ALDH1A1 (0.69) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL940131 | 0.81 | ALDH1A1 (0.60) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL7291408 | 0.81 | ALDH1A1 (0.60) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL8110068 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL29975597 | 0.81 | FOLH1 (0.66) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL166927 | 0.81 | FOLH1 (0.66) | ALDH1A1ADRB2HTTMAPTLMNA | |
| SCHEMBL28403638 | 0.81 | ALDH1A1 (0.64) | ALDH1A1ADRB2HTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148539-B1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION INC (US) | 2021-02-17 | — | — | EP | disclosed |