SCHEMBL29975597

SCHEMBL29975597

O=C(O)c1ccccc1CCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.66
▸ ALDH1A1 P00352 7/20 0.64
▸ ADRB2 P07550 1/20 0.64
▸ HTT P42858 1/20 0.57
▸ MAPT P10636 1/20 0.57
▸ TSHR P16473 3/20 0.55
▸ LMNA P02545 2/20 0.55
▸ KDM4E B2RXH2 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ KMT2A Q03164 2/20 0.54
▸ ALOX15 P16050 1/20 0.52
▸ SCN1A P35498 1/20 0.51
▸ SCN2A Q99250 1/20 0.51
▸ SCN3A Q9NY46 1/20 0.51
▸ MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL166927 1.00 FOLH1 (0.66) FOLH1ALDH1A1ADRB2HTTMAPT
Hydrochloric Acid SCHEMBL7699238 0.98 FOLH1 (0.63) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL8702953 0.98 FOLH1 (0.63) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL8698803 0.93 FOLH1 (0.58) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL30365583 0.91 FOLH1 (0.76) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL70392 0.91 FOLH1 (0.76) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL7764255 0.89 TSHR (0.72) FOLH1ALDH1A1ADRB2HTTMAPT
SCHEMBL11710027 0.88 FOLH1 (0.61) FOLH1ALDH1A1ADRB2MAPTTSHR
SCHEMBL20162476 0.88 FOLH1 (0.61) FOLH1ALDH1A1ADRB2MAPTTSHR
Hydrochloric Acid SCHEMBL8327538 0.88 KMT2A (0.56) FOLH1ALDH1A1ADRB2HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4692092-A1 NOVEL COMPOUNDS WITH MTORC2-INHIBITORY ACTIVITY AND USES THEREOF Aliad Biopharma (KR) 2026-02-11 — — EP disclosed
WO-2024205377-A1 NOVEL COMPOUNDS WITH MTORC2-INHIBITORY ACTIVITY AND USES THEREOF 알리아드바이오파마 주식회사 2024-10-03 — — WO disclosed
US-20230095374-A1 MEROTERPENOID COMPOUNDS FOR USE IN THE PREVENTION AND TREATMENT OF A NEUROLOGICAL DISORDER GLIAPHARM SA (CH) 2023-03-30 — — US disclosed
US-11510890-B2 Meroterpenoid compounds for use in the prevention and treatment of a neurological disorder SOCIETE DES PRODUITS NESTLE S.A. (CH) 2022-11-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11510890-B2 Meroterpenoid compounds for use in the prevention and treatment of a neurological disorder NLN, SLC6A13, SLC6A11 FOLH1 1482/4885ALDH1A1 1446/4885ADRB2 1774/4885
US-20230095374-A1 MEROTERPENOID COMPOUNDS FOR USE IN THE PREVENTION AND TREATMENT OF A NEUROLOGICAL DISORDER NLN, SLC6A13, SLC6A11 FOLH1 1482/4885ALDH1A1 1446/4885ADRB2 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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