Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 4/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28193722 | 0.98 | ALDH1A1 (0.58) | ALDH1A1ADRB2KMT2ASIRT2HTT | |
| Trifluoroacetic Acid SCHEMBL15568420 | 0.90 | ALDH1A1 (0.51) | ALDH1A1ADRB2KMT2ASIRT2HTT | |
| SCHEMBL4735612 | 0.90 | ALDH1A1 (0.54) | ALDH1A1ADRB2KMT2ASIRT2MAPT | |
| SCHEMBL29410986 | 0.89 | BID (0.51) | ALDH1A1ADRB2KMT2ASIRT2MAPT | |
| SCHEMBL3376462 | 0.89 | SIRT2 (0.50) | ALDH1A1ADRB2KMT2ASIRT2MAPT | |
| SCHEMBL11901439 | 0.88 | SIRT2 (0.64) | ALDH1A1ADRB2KMT2ASIRT2MAPT | |
| SCHEMBL5723969 | 0.87 | CYP19A1 (0.50) | ALDH1A1ADRB2KMT2ASIRT2HTT | |
| SCHEMBL11782261 | 0.86 | SIRT2 (0.48) | ALDH1A1ADRB2KMT2ASIRT2HTT | |
| SCHEMBL21357052 | 0.86 | ALDH1A1 (0.61) | ALDH1A1ADRB2KMT2ASIRT2HTT | |
| SCHEMBL4354269 | 0.86 | KDR (0.56) | ALDH1A1ADRB2KMT2ASIRT2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167556-A | Thio-hydantoin androgen receptor antagonist for treating cancer | 詹森药业有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-107624110-A | Inhibitor of lysyloxidase sample 2 and application thereof | 法玛克亚公司 | 2018-01-23 | — | — | CN | claimed |
| CN-105294597-B | Benzothiazine derivatives and its synthetic method and application | 华东师范大学 | 2017-11-24 | — | — | CN | claimed |
| EP-2252296-A1 | 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | Wyeth LLC (US) | 2010-11-24 | — | — | EP | claimed |
| WO-2010102157-A1 | MOLECULAR PREDICTORS OF BIOLOGICAL RESPONSE TO A CENPE INHIBITOR IN CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-09-10 | — | — | WO | claimed |
| WO-2009091788-A1 | 3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-07-23 | — | — | WO | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2003047572-A1 | USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-12 | — | — | WO | claimed |
| CN-1333698-A | Combination chemotherapy | WARNER LAMBERT CO (US) | 2002-01-30 | — | — | CN | claimed |
| EP-0848700-A1 | ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES | BAYER AG (DE) | 1998-06-24 | — | — | EP | claimed |
| WO-1997008135-A1 | ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | claimed |
| CN-116096363-A | Coronavirus proliferation method | 花王株式会社 | 2023-05-09 | — | — | CN | disclosed |
| WO-2022195522-A1 | INHIBITORS OF ANO6 AND THEIR USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-09-22 | — | — | WO | disclosed |
| WO-2022157686-A1 | INHIBITORS OF ANOCTAMIN 6 PROTEIN AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-07-28 | — | — | WO | disclosed |
| WO-2003072098-A1 | USE OF SUBSTITUTED 3-PHENYL-5-ALKOXY-1,3,4-OXDIAZOLE-2-ONE FOR PRODUCING MEDICAMENTS THAT INHIBIT PANCREATIC LIPASE | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-09-04 | — | — | WO | disclosed |
| US-6492363-B2 | FOR THERAPY OF CANCER AND OTHER PROLIFERATIVE DISEASES SUCH AS INFLAMMATION, PSORIASIS AND RESTENOSIS, AS WELL AS STROKE, HEART FAILURE, AND IMMUNODEFICIENCY DISORDERS | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-4873335-A | 3-phenethyl-2-benzene-amides or aza-derivatives thereof | SCHERING CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | ALDH1A1 123/4885ADRB2 3735/4885KMT2A 3181/4885 |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ALDH1A1 170/4885ADRB2 3565/4885KMT2A 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.