Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19637285 | 1.00 | CTSL (0.40) | CTSLCTSBCTSKL3MBTL1TAAR1 | |
| SCHEMBL19617897 | 0.78 | TRPV6 (0.55) | CTSLCTSBCTSK | |
| SCHEMBL19616936 | 0.78 | TRPV6 (0.55) | CTSLCTSBCTSK | |
| SCHEMBL5209947 | 0.77 | TSHR (0.50) | CTSLCTSBCTSKL3MBTL1TAAR1 | |
| SCHEMBL20466290 | 0.74 | SSTR4 (0.42) | CTSLCTSBCTSKL3MBTL1GBA1 | |
| SCHEMBL13662029 | 0.72 | TSHR (0.42) | CTSLCTSBCTSKL3MBTL1TAAR1 | |
| SCHEMBL17243613 | 0.72 | SSTR4 (0.50) | CTSLCTSBCTSKGBA1UGCG | |
| SCHEMBL13662039 | 0.71 | CTSL (0.41) | CTSLCTSBCTSKL3MBTL1TAAR1 | |
| SCHEMBL19637287 | 0.71 | TSHR (0.40) | CTSLCTSBCTSKL3MBTL1TAAR1 | |
| SCHEMBL24207209 | 0.71 | TSHR (0.50) | CTSLCTSBCTSKTAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458445-B1 | KRAS G12C INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2021-02-17 | — | — | EP | disclosed |