SCHEMBL19616936

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19617897	1.00	TRPV6 (0.55)	TRPV6HTR1DHTR1BDRD2HTR2A
	SCHEMBL21908568	0.83	TRPV6 (0.50)	TRPV6HTR1DHTR1BHRH3CTSL
	SCHEMBL19947782	0.83	TRPV6 (0.50)	TRPV6HTR1DHTR1BHRH3CTSL
	SCHEMBL19948638	0.83	TRPV6 (0.50)	TRPV6HTR1DHTR1BHRH3CTSL
	SCHEMBL22110284	0.83	CHRNB2 (0.57)	KCNH2CHRNB2CHRNA5CHRNA7CHRNA4
	SCHEMBL14502963	0.83	CHRNB2 (0.57)	KCNH2CHRNB2CHRNA5CHRNA7CHRNA4
	SCHEMBL6166949	0.83	TRPV6 (0.51)	TRPV6HTR1DHTR1BHRH3CTSL
	SCHEMBL22994657	0.78	CTSL (0.40)	CTSLCTSBCTSK
	SCHEMBL19637285	0.78	CTSL (0.40)	CTSLCTSBCTSK
	SCHEMBL23546142	0.78	LTA4H (0.46)	TRPV6HTR1DHTR1BHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.