Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 7/20 | 0.34 |
| ▸ | MMP3 | P08254 | 7/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | Q9HBH1 | 1/20 | 0.34 | |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18572996 | 0.85 | CA2 (0.41) | CA2CA1DPP7SLC15A1MAPK1 | |
| SCHEMBL20411668 | 0.85 | CA2 (0.41) | CA2CA1DPP7SLC15A1MAPK1 | |
| SCHEMBL20411635 | 0.85 | CA2 (0.41) | CA2CA1DPP7SLC15A1MAPK1 | |
| SCHEMBL22199502 | 0.75 | CA1 (0.34) | CA2CA1DPP7SLC15A1MMP2 | |
| SCHEMBL22861972 | 0.74 | CA2 (0.39) | CA2CA1MAPK1PDFSLC1A3 | |
| SCHEMBL19993074 | 0.73 | GPR84 (0.48) | CA2CA1MAPK1SLC1A2SLC1A1 | |
| SCHEMBL19546495 | 0.72 | HDAC7 (0.45) | CA2CA1MMP2MMP3MMP1 | |
| SCHEMBL14297651 | 0.72 | GPR84 (0.52) | CA2SLC1A2SLC1A1 | |
| SCHEMBL25090841 | 0.71 | CA2 (0.57) | CA2CA1MAPK1MMP2MMP3 | |
| SCHEMBL23449935 | 0.70 | CA1 (0.48) | CA2CA1DPP7SLC15A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778622-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-02-17 | — | — | EP | disclosed |