Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027633 | 0.77 | KCNA5 (0.56) | CXCR2KCNA5MALT1DRD2BCHE | |
| SCHEMBL26936105 | 0.72 | HPGD (0.64) | NAMPTDRD2 | |
| SCHEMBL1657927 | 0.72 | ESRRG (0.56) | CXCR2KCNA5MALT1BCHEIDO1 | |
| SCHEMBL4059012 | 0.71 | HPGD (0.56) | KCNA5MALT1BCHEIDO1SIGMAR1 | |
| SCHEMBL14691000 | 0.71 | KCNA5 (0.46) | CXCR2KCNA5MALT1CSNK1DBCHE | |
| SCHEMBL14690580 | 0.70 | CRBN (0.51) | CXCR2KCNA5MALT1BCHEIDO1 | |
| SCHEMBL9743749 | 0.70 | KCNA5 (0.56) | CXCR2KCNA5MALT1DRD2BCHE | |
| SCHEMBL14691066 | 0.70 | DRD2 (0.45) | CXCR2KCNA5MALT1DRD2CSNK1D | |
| SCHEMBL9540574 | 0.69 | KCNA5 (0.58) | CXCR2KCNA5MALT1DRD2BCHE | |
| SCHEMBL284764 | 0.69 | SMN1; SMN2 (0.55) | MALT1BCHENQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110207701-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207701-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | CXCR2 1176/4885NAMPT 516/4885KCNA5 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.