Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23020684 | 0.89 | PNMT (0.38) | PNMT | |
| Trifluoroacetic Acid SCHEMBL29192027 | 0.82 | KDM1A (0.39) | KDM1A | |
| Trifluoroacetic Acid SCHEMBL26606130 | 0.77 | SLC1A2 (0.35) | KDM1A | |
| Trifluoroacetic Acid SCHEMBL4307037 | 0.72 | PKM (0.36) | KDM1A | |
| SCHEMBL4649924 | 0.70 | — | — | |
| Trifluoroacetic Acid SCHEMBL21598176 | 0.68 | KDM1A (0.33) | KDM1A | |
| Trifluoroacetic Acid SCHEMBL27673776 | 0.68 | CRBN (0.55) | KDM1A | |
| SCHEMBL15606429 | 0.67 | EGLN1 (0.47) | — | |
| SCHEMBL532127 | 0.67 | EGLN1 (0.47) | — | |
| SCHEMBL16967412 | 0.67 | EGLN1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032323-A1 | FUSED PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROTIC DISEASES | GALAPAGOS NV (BE) | 2021-02-25 | — | — | WO | disclosed |
| EP-3782997-A1 | FUSED PYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROTIC DISEASES | Galapagos N.V. (BE) | 2021-02-24 | — | — | EP | disclosed |