Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230028 | 0.96 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9173067 | 0.94 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26918976 | 0.94 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9067880 | 0.94 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1536163 | 0.88 | THRB (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.85 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11600594 | 0.83 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9162964 | 0.83 | TSHR (0.69) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28079051 | 0.81 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL339022 | 0.81 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533854-B | Silicon modified acrylic resin and application thereof | 上海亿祺化工技术有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-109803826-B | Laminate and method for producing same | 信越化学工业株式会社 | 2021-05-11 | — | — | CN | disclosed |
| CN-108472685-B | Method for producing laminate | 信越化学工业株式会社 | 2021-02-02 | — | — | CN | disclosed |
| CN-111533854-A | Silicon modified acrylic resin and application thereof | 上海亿祺化工技术有限公司 | 2020-08-14 | — | — | CN | disclosed |
| EP-3045506-B1 | ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE | SHINETSU CHEMICAL CO (JP) | 2020-03-04 | — | — | EP | disclosed |
| US-20190291394-A1 | LAMINATED BODY AND PRODUCTION METHOD THEREFOR | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-09-26 | — | — | US | disclosed |
| EP-3527366-A1 | LAMINATED BODY AND PRODUCTION METHOD THEREFOR | Shin-Etsu Chemical Co., Ltd. (JP) | 2019-08-21 | — | — | EP | disclosed |
| US-10196409-B2 | Organosilicon compound and curable composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-02-05 | — | — | US | disclosed |
| EP-3210988-B1 | ORGANOSILICON COMPOUND AND CURABLE COMPOSITION | SHINETSU CHEMICAL CO (JP) | 2018-06-20 | — | — | EP | disclosed |
| EP-3210988-A1 | ORGANOSILICON COMPOUND AND CURABLE COMPOSITION | Shin-Etsu Chemical Co., Ltd. (JP) | 2017-08-30 | — | — | EP | disclosed |
| US-20170240573-A1 | ORGANOSILICON COMPOUND AND CURABLE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| US-20160208132-A1 | ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-07-21 | — | — | US | disclosed |
| EP-3045506-A1 | ACTINIC ENERGY RADIATION-CURABLE ACRYLIC SILICONE RESIN COMPOSITION AND COATED ARTICLE | Shin-Etsu Chemical Co., Ltd. (JP) | 2016-07-20 | — | — | EP | disclosed |
| EP-0769513-B1 | Curable resin composition | NIPPON PAINT CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5674569-A | CURING UNDERCOATINGS, CLEAR TOP COATINGS CONCURRENTLY OR SEPARATLY, THE TOP COATINGS COMPRISING A BLEND OF A RESIN WITH PLURAL HYDROSILYL GROUP OR A POLYHYDROGENSILOXANE HOMO-OR COPOLYMER | NIPPON PAINT CO., LTD. (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0769513-A1 | Curable resin composition | NIPPON PAINT CO., LTD. (JP) | 1997-04-23 | — | — | EP | disclosed |
| US-5599883-A | COATING MIXTURES ALSO CONTAINING HYDROSILATION CATALYST | NIPPON PAINT CO., LTD. (JP) | 1997-02-04 | — | — | US | disclosed |
| EP-0702068-A1 | Method of forming multilayer coatings on a substrate | Nippon Paint Co., Ltd. (JP) | 1996-03-20 | — | — | EP | disclosed |
| EP-0630943-A2 | Curable resin composition | Nippon Paint Co., Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196409-B2 | Organosilicon compound and curable composition | MASTL, PIEZO1, MCM6 | TSHR 3198/4885THRB 2691/4885POLB 1711/4885 |
| US-20170240573-A1 | ORGANOSILICON COMPOUND AND CURABLE COMPOSITION | MASTL, PIEZO1, MCM6 | TSHR 3198/4885THRB 2691/4885POLB 1711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.