Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 3/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16920091 | 0.92 | TSHR (0.35) | TSHR | |
| SCHEMBL23002895 | 0.88 | TSHR (0.46) | TSHRALDH1A1ALOX15 | |
| SCHEMBL13324456 | 0.87 | TSHR (0.39) | TSHRTLR2ACHEALOX15 | |
| SCHEMBL274739 | 0.86 | TSHR (0.47) | TSHRTLR2ACHEEPHX1 | |
| SCHEMBL23031224 | 0.85 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL13872066 | 0.83 | ACHE (0.47) | TSHRACHEALOX15 | |
| SCHEMBL14529602 | 0.83 | TSHR (0.45) | TSHRACHEALOX15 | |
| SCHEMBL16474278 | 0.83 | TSHR (0.40) | TSHRALDH1A1TLR2 | |
| SCHEMBL14654921 | 0.82 | TSHR (0.44) | TSHRTLR2ACHEEPHX1 | |
| SCHEMBL14016494 | 0.82 | TSHR (0.41) | TSHRALDH1A1ACHEEPHX1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | VOCO GMBH (DE) | 2024-05-28 | — | — | US | disclosed |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992538-B2 | Polymerizable dental composition based on condensed silanes | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885ALDH1A1 1481/4885TLR2 2067/4885 |
| US-20210052469-A1 | POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES | NCAPH, RCC1, NCAPD2 | TSHR 4596/4885ALDH1A1 1481/4885TLR2 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.