Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430443 | 0.84 | EPHX2 (0.52) | DPP4EPHX2TOP2A | |
| SCHEMBL12354573 | 0.83 | DPP4 (0.53) | DPP4EPHX2CA12CA2CA7 | |
| SCHEMBL2300337 | 0.82 | EPHX2 (0.53) | DPP4EPHX2TOP2AMEN1KMT2A | |
| SCHEMBL12735376 | 0.80 | DPP4 (0.56) | DPP4EPHX2KMT2AEPHX1 | |
| SCHEMBL12962021 | 0.79 | EPHX2 (0.68) | EPHX2MEN1KMT2AEPHX1 | |
| SCHEMBL158816 | 0.78 | DPP4 (0.58) | DPP4EPHX2EPHX1 | |
| Hydrochloric Acid SCHEMBL27500984 | 0.76 | DPP4 (0.56) | DPP4EPHX2EPHX1 | |
| SCHEMBL24267663 | 0.76 | GAA (0.45) | DPP4EPHX2TOP2A | |
| SCHEMBL27004555 | 0.76 | ATM (0.58) | EPHX2ATMMEN1KMT2AEPHX1 | |
| SCHEMBL16365977 | 0.73 | EPHX2 (0.61) | EPHX2CA12CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529808-A | Chiral amide compound, as well as preparation method and application thereof | SHANGHAI INST TECHNOLOGY | 2015-04-22 | — | — | CN | disclosed |
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |