Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267663 | 0.93 | GAA (0.45) | EPHX2TOP2ADPP4 | |
| SCHEMBL27974243 | 0.85 | DPP4 (0.50) | EPHX2DPP4 | |
| SCHEMBL7438003 | 0.84 | DPP4 (0.53) | EPHX2TOP2ADPP4 | |
| SCHEMBL9298447 | 0.83 | EPHX2 (0.60) | EPHX2TOP2A | |
| SCHEMBL10487625 | 0.83 | EPHX2 (0.41) | EPHX2TOP2A | |
| SCHEMBL11329105 | 0.81 | EPHX2 (0.65) | EPHX2 | |
| SCHEMBL11439126 | 0.78 | EPHX2 (0.58) | EPHX2LMNA | |
| SCHEMBL2300337 | 0.78 | EPHX2 (0.53) | EPHX2TOP2ADPP4 | |
| SCHEMBL12735376 | 0.76 | DPP4 (0.56) | EPHX2DPP4 | |
| SCHEMBL3712266 | 0.75 | LMNA (0.58) | EPHX2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |
| EP-0029658-A1 | Salts of dihalo-2-quinoxaline carboxylic acids, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |