Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.47 |
| ▸ | THRA | P10827 | 13/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23003820 | 0.96 | THRA (0.50) | THRBTHRAPDK2PDE4APDE4B | |
| SCHEMBL23003611 | 0.91 | THRB (0.56) | THRBTHRAPDE4APDE4BPDE4C | |
| SCHEMBL25528043 | 0.91 | THRA (0.48) | THRBTHRAPDK2PDE4APDE4B | |
| SCHEMBL25528053 | 0.88 | THRB (0.49) | THRBTHRAPDK2GAA | |
| SCHEMBL23003720 | 0.87 | THRB (0.48) | THRBTHRAPDK2 | |
| SCHEMBL23003663 | 0.87 | THRA (0.50) | THRBTHRAPDE4APDE4BPDE4C | |
| SCHEMBL25528526 | 0.86 | THRA (0.52) | THRBTHRAPDE4APDE4BPDE4C | |
| SCHEMBL25528034 | 0.86 | THRB (0.50) | THRBTHRAPDK2PDE4APDE4B | |
| SCHEMBL23003824 | 0.86 | THRA (0.47) | THRBTHRAPDK2 | |
| SCHEMBL23003700 | 0.85 | THRA (0.60) | THRBTHRAPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-11667606-B2 | Thyromimetics | AUTOBAHN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210053917-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2021-02-25 | — | — | US | disclosed |
| US-20210053917-A1 | NOVEL THYROMIMETICS | AUTOBAHN THERAPEUTICS, INC. | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667606-B2 | Thyromimetics | TPO, TSHR, TTR | THRB 9/4885THRA 4/4885PDK2 2532/4885 |
| US-20210053917-A1 | NOVEL THYROMIMETICS | TPO, TSHR, CHRM1 | THRB 12/4885THRA 11/4885PDK2 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.