Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 4/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL23004401 | 0.95 | OPRM1 (0.36) | OPRM1LMNAADH1BADH1CADH1A | |
| Hydrochloric Acid SCHEMBL23004053 | 0.95 | OPRM1 (0.36) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL23004310 | 0.90 | OPRM1 (0.32) | OPRM1LMNA | |
| SCHEMBL24409398 | 0.76 | OPRM1 (0.44) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL24394272 | 0.76 | OPRM1 (0.44) | OPRM1LMNAADH1BADH1CADH1A | |
| Bromide SCHEMBL28432455 | 0.76 | GPR84 (0.42) | LMNAFDPSGPR84SPHK1 | |
| SCHEMBL11299774 | 0.74 | OPRM1 (0.42) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL386845 | 0.73 | — | — | |
| SCHEMBL23879419 | 0.73 | SPHK1 (0.43) | OPRM1LMNAADH1BADH1CADH1A | |
| SCHEMBL4309182 | 0.73 | GPR84 (0.43) | LMNAFDPSGPR84SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623971-B2 | Freestanding ion gel and method for preparing the same | Research & Business Foundation Sungkyunkwan University (KR) | 2023-04-11 | — | — | US | disclosed |
| US-20210054127-A1 | FREESTANDING ION GEL AND METHOD FOR PREPARING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2021-02-25 | — | — | US | disclosed |