⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527026 | 0.97 | LMNA (0.41) | — | |
| SCHEMBL27709118 | 0.97 | LMNA (0.41) | — | |
| SCHEMBL387573 | 0.92 | — | — | |
| SCHEMBL385646 | 0.80 | — | — | |
| SCHEMBL28549540 | 0.77 | EPHX1 (0.40) | — | |
| SCHEMBL387519 | 0.77 | OPRM1 (0.39) | — | |
| SCHEMBL27890930 | 0.75 | LMNA (0.39) | — | |
| SCHEMBL6751058 | 0.74 | — | — | |
| SCHEMBL7308649 | 0.74 | — | — | |
| Bromide SCHEMBL23004331 | 0.73 | OPRM1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8180444-B2 | Enhanced PhotoDynamic Therapy with immune system assist | BIOLITEC PHARMA MARKETING LTD (MY) | 2012-05-15 | — | — | US | disclosed |
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8067396-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | disclosed |
| US-7910617-B2 | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound | SANKYO COMPANY, LIMITED (JP) | 2011-03-22 | — | — | US | disclosed |
| CN-1921847-B | Amino alcohol compound | SANKYO CO | 2010-06-16 | — | — | CN | disclosed |
| US-20100035842-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20090326038-A1 | Method for treating a immunology-related disease | SANKYO COMPANY, LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-7638551-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2009-12-29 | — | — | US | disclosed |
| EP-1471054-B1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-7521551-B2 | Chlorins possessing fused ring systems useful as photoselective compounds for photodynamic therapy | MIRAVANT PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-0804439-A1 | BETA, BETA '-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM BETA ,BETA '-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-11-05 | — | — | EP | disclosed |
| CN-1161697-A | Beta, beta '-dihydroxy meso-substituted chlorins, isobacteriochlorins, bacteriochlorins, and methods of making said compounds from beta, beta' -unsubstituted tetrapyrrolic macrocycles | UNIV BRITISH COLUMBIA (CA) | 1997-10-08 | — | — | CN | disclosed |
| EP-0794954-A1 | MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | QUADRA LOGIC TECHNOLOGIES INC. (CA) | 1997-09-17 | — | — | EP | disclosed |
| US-5656756-A | PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY, ANTITUMOR AGENTS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-08-12 | — | — | US | disclosed |
| US-5648485-A | PORPHYRIN COMPOUNDS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-07-15 | — | — | US | disclosed |
| WO-1996016966-A1 | MESO-MONOIODO-SUBSTITUTED TETRAMACROCYCLIC COMPOUNDS AND METHODS FOR MAKING AND USING THE SAME | QUADRA LOGIC TECHNOLOGIES, INC. (CA) | 1996-06-06 | — | — | WO | disclosed |
| WO-1996013504-A1 | β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1996-05-09 | — | — | WO | disclosed |
| WO-1995029914-A1 | A METHOD OF SYNTHESIZING 5,15-DIARYLBENZOCHLORIN-7-ONE COMPOUNDS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1995-11-09 | — | — | WO | disclosed |
| US-4357476-A | Nonylamines | CIBA GEIGY CORPORATION, N.Y. (US) | 1982-11-02 | — | — | US | disclosed |
| US-4139560-A | Nonylamines | CIBA GEIGY CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |