Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400752 | 0.79 | MAOB (0.52) | AGXTIDO1CYP2A6CYP1A2TAAR1 | |
| SCHEMBL161348 | 0.79 | ALDH1A1 (0.53) | AGXTIDO1CYP2A6TAAR1TP53 | |
| SCHEMBL261253 | 0.78 | MAOB (0.61) | IDO1MAOBTP53CA1CA2 | |
| SCHEMBL334261 | 0.78 | MAOB (0.61) | IDO1MAOBTP53CA1CA2 | |
| SCHEMBL145088 | 0.78 | MAOB (0.61) | IDO1MAOBTP53CA1CA2 | |
| SCHEMBL19439522 | 0.76 | THRB (0.46) | TP53ACHECA2LMNA | |
| SCHEMBL7569322 | 0.74 | IDO1 (0.41) | AGXTIDO1CYP2A6CYP1A2TAAR1 | |
| SCHEMBL10635864 | 0.73 | AGXT (0.50) | AGXTIDO1CYP2A6CYP1A2TAAR1 | |
| SCHEMBL2132369 | 0.73 | AGXT (0.50) | AGXTIDO1CYP2A6CYP1A2TAAR1 | |
| SCHEMBL30753808 | 0.72 | AGXT (0.40) | AGXTIDO1CYP2A6CYP1A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536698-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | Syngenta Participations AG (CH) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011101402-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |