SCHEMBL261253

SCHEMBL261253

O=[C]/C=C\Cc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.61
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ARG2 P78540 1/20 0.47
TOP1 P11387 1/20 0.43
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TSHR P16473 1/20 0.39
CALM1 P0DP23 1/20 0.36
MAPK1 P28482 1/20 0.36
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH7 P40394 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
IDO1 P14902 2/20 0.34
EPHX2 P34913 1/20 0.34
AKR1B1 P15121 1/20 0.34
KCNH2 Q12809 2/20 0.34
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145088 1.00 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL334261 1.00 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL6803900 0.85 MAOB (0.54) MAOBCA1CA2ARG2TOP1
SCHEMBL6803903 0.85 MAOB (0.54) MAOBCA1CA2ARG2TOP1
SCHEMBL5254612 0.78 GPR52 (0.50) HCAR2
SCHEMBL146890 0.78 GPR52 (0.50) HCAR2
SCHEMBL2300477 0.78 AGXT (0.39) MAOBCA1CA2IDO1TP53
SCHEMBL10563302 0.77 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL9718255 0.77 MAOB (0.61) MAOBCA1CA2ARG2TOP1
SCHEMBL155054 0.77 MAOB (1.00) MAOBCA1CA2ARG2TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9558863-B2 Electrically conductive polymers with enhanced conductivity KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2017-01-31 US disclosed
US-9243111-B2 Water-soluble electrically conductive polymers KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2016-01-26 US disclosed
US-20150083977-A1 ELECTRICALLY CONDUCTIVE POLYMERS WITH ENHANCED CONDUCTIVITY KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2015-03-26 US disclosed
US-8920681-B2 Electrically conductive polymers with enhanced conductivity KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2014-12-30 US disclosed
US-20140077135-A1 WATER-SOLUBLE ELECTRICALLY CONDUCTIVE POLYMERS KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2014-03-20 US disclosed
US-8536300-B2 Photocrosslinkable electrically conductive polymers KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2013-09-17 US disclosed
US-8535571-B2 Water-soluble electrically conductive polymers KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2013-09-17 US disclosed
US-8134023-B2 Preparation of pregabalin and related compounds PFIZER INC (US) 2012-03-13 US disclosed
US-20120015412-A1 Preparation of Pregabalin and Related Compounds PFIZER INC 2012-01-19 US disclosed
US-8044227-B2 Preparation of pregabalin and related compounds PFIZER INC. (US) 2011-10-25 US disclosed
US-6110933-A AN ENZYME INHIBITOR TREATING PANCREATITIS, HEPATITIS, CHRONIC RENAL FAILURE, ENDOTOXIN SHOCK, GRAM-NEGATIVE SEPTIC SHOCK, ARTHRITIS, RESPIRATORY DISEASE, HEART DISEASE, ALLERGIC DISEASE, THROMBOSIS, ARTERIOSCLEROSIS, PAIN FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-08-29 US disclosed
US-6096735-A Benzoheterocyclic derivatives OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 2000-08-01 US disclosed
WO-2000000220-A1 PHARMACEUTICAL COMPOSITION CONTAINING AN ESTER OR AMIDE PLA2 INHIBITOR FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-01-06 WO disclosed
EP-0741697-B1 AMINO ACID DERIVATIVES AND THEIR USE AS PHOSPHOLIPASE A2 INHIBITORS FUJISAWA PHARMACEUTICAL CO (JP) 1999-09-15 EP disclosed
EP-0854863-A1 ESTERS AND AMIDES AS PLA2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-07-29 EP disclosed
EP-0765314-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-02 EP disclosed
WO-1997003951-A1 ESTERS AND AMIDES AS PLA2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-02-06 WO disclosed
EP-0741697-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PHOSPHOLIPASE A2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-11-13 EP disclosed
WO-1995034540-A1 BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1995-12-21 WO disclosed
WO-1995019959-A1 AMINO ACID DERIVATIVES AND THEIR USE AS PHOSPHOLIPASE A2 INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-07-27 WO disclosed