Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345597 | 0.87 | NPC1 (0.48) | MAPK7MCHR1NPC1RAB9AMAPT | |
| SCHEMBL2303204 | 0.82 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL24891825 | 0.77 | RAB9A (0.64) | ITGB3ITGA2BNPC1RAB9AMAPT | |
| SCHEMBL2300598 | 0.76 | HRH4 (0.51) | ITGB3ITGA2BNPC1RAB9AMAPT | |
| SCHEMBL17607243 | 0.75 | MAPK7 (0.47) | MAPK7NPC1RAB9A | |
| SCHEMBL17801122 | 0.74 | NPC1 (0.75) | ITGB3ITGA2BNPC1RAB9AMAPT | |
| SCHEMBL1663115 | 0.73 | ALDH1A1 (0.66) | ITGB3ITGA2BNPC1RAB9AMAPT | |
| SCHEMBL8769785 | 0.73 | RAB9A (0.59) | ITGB3ITGA2BNPC1RAB9AMAPT | |
| SCHEMBL24891642 | 0.73 | MAPT (0.61) | ITGB3ITGA2BNPC1RAB9AMAPT | |
| SCHEMBL30182512 | 0.73 | MAPT (0.61) | ITGB3ITGA2BNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350311-A1 | DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | Via Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |