Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640110 | 0.92 | SMPD1 (0.44) | TSHRSMPD1PLA2G4B | |
| SCHEMBL4640654 | 0.90 | SMPD1 (0.46) | THRATHRBTSHRSMPD1PLA2G4B | |
| SCHEMBL27700898 | 0.85 | KMT2A (0.47) | HTTLMNATSHRSMN1; SMN2MEN1 | |
| SCHEMBL22954894 | 0.83 | ALDH1A1 (0.44) | HTTLMNAHPGD | |
| SCHEMBL2203559 | 0.80 | ALDH1A1 (0.56) | HTTLMNASMN1; SMN2GAAHPGD | |
| SCHEMBL13683800 | 0.78 | ALDH1A1 (0.63) | THRATHRBPLA2G4B | |
| SCHEMBL14418357 | 0.78 | MEN1 (0.48) | SMPD1MEN1GAAKMT2A | |
| SCHEMBL12882280 | 0.78 | MAPT (0.44) | HTTLMNATSHRSMN1; SMN2SMPD1 | |
| SCHEMBL2450255 | 0.78 | L3MBTL1 (0.47) | THRATHRBTSHRSMPD1GAA | |
| SCHEMBL14195830 | 0.77 | MAOB (0.62) | THRATHRBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030703-A1 | DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-18 | — | — | WO | disclosed |