SCHEMBL2450255

SCHEMBL2450255

CCCCCCCCCCCCOc1ccc(Cl)c(NC=O)c1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
SMPD1 P17405 3/20 0.45
TP53 P04637 2/20 0.44
GAA P10253 1/20 0.44
NR5A1 Q13285 1/20 0.43
PLA2G4B P0C869 1/20 0.42
TSHR P16473 2/20 0.42
PLA2G2A P14555 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4640654 0.82 SMPD1 (0.46) THRATHRBSMPD1TP53NR5A1
SCHEMBL8957704 0.81 L3MBTL1 (0.47) L3MBTL1THRATHRBSMPD1TP53
SCHEMBL4640110 0.80 SMPD1 (0.44) SMPD1TP53NR5A1PLA2G4BTSHR
SCHEMBL9172922 0.78 NPC1 (0.51)
SCHEMBL8003361 0.78 NPC1 (0.51)
SCHEMBL3139745 0.78 NPC1 (0.51)
SCHEMBL23007648 0.78 THRA (0.47) THRATHRBSMPD1GAAPLA2G4B
SCHEMBL20503253 0.77 KDM4E (0.63) L3MBTL1THRATHRBTP53NR5A1
SCHEMBL9868736 0.76 HDAC3 (0.44) SMPD1
SCHEMBL5948127 0.76 NPC1 (0.58) TP53NR5A1PLA2G4BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP claimed
EP-1980908-B1 Use of silver halide photographic material and image forming method FUJIFILM CORP (JP) 2011-09-07 EP disclosed
US-7592133-B2 Silver halide photographic material and image forming method using the same FUJIFILM CORPORATION (JP) 2009-09-22 US disclosed
US-20080268385-A1 Silver halide photographic material and image forming method using the same FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
EP-1980908-A1 Silver halide photographic material and image forming method using the same FUJIFILM Corporation (JP) 2008-10-15 EP disclosed
US-20080214810-A1 DYE-FORMING COUPLER, SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL, AND AZOMETHINE DYE COMPOUND UEHIRA SHIGEKI 2008-09-04 US disclosed
US-7365199-B2 Dye-forming coupler, silver halide photographic light-sensitive material, and azomethine dye compound FUJIFILM CORPORATION (JP) 2008-04-29 US disclosed
US-20060223013-A1 Silver halide color photographic photosensitive material and image forming method FUJI PHOTO FILM CO., LTD. 2006-10-05 US disclosed
US-7112400-B2 Silver halide color photographic photosensitive material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2006-09-26 US disclosed
US-7008760-B1 Silver halide color photographic light-sensitive material and method of forming a color image FUJI PHOTO FILM CO., LTD. (JP) 2006-03-07 US disclosed
EP-0459349-A1 Silver halide color negative photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-04 EP disclosed
US-5064750-A Naphthol amido coupler, bleaching bath of diamino propane teraacetato iron complex FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
EP-0301477-B1 SILVER HALIDE COLOR PHOTOSENSITIVE MATERIAL AND METHOD OF PROCESSING THEREOF Fuji Photo Film Co., Ltd. (JP) 1991-04-03 EP disclosed
EP-0370357-A1 Process for producing 3-iminonitriles FUJI PHOTO FILM CO., LTD. (JP) 1990-05-30 EP disclosed
EP-0313083-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0301477-A2 Silver halide color photosensitive material and method of processing thereof Fuji Photo Film Co., Ltd. (JP) 1989-02-01 EP disclosed
EP-0295632-A2 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-12-21 EP disclosed
EP-0261244-A1 COLOR IMAGE FORMING PROCESS FUJI PHOTO FILM CO., LTD. (JP) 1988-03-30 EP disclosed
EP-0176804-A1 Silver halide color photograhic materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-09 EP disclosed
EP-0170164-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214810-A1 DYE-FORMING COUPLER, SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL, AND AZOMETHINE DYE COMPOUND IK, CBR1, CNKSR1 L3MBTL1 1155/4885THRA 2505/4885THRB 3577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.