Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143661 | 0.88 | SPHK1 (0.67) | SPHK1SPHK2S1PR4S1PR1S1PR3 | |
| SCHEMBL29880747 | 0.86 | SPHK1 (0.56) | SPHK1SPHK2CTSKS1PR4S1PR1 | |
| SCHEMBL1312367 | 0.86 | SPHK1 (0.60) | SPHK1SPHK2CTSKS1PR4S1PR1 | |
| SCHEMBL1315000 | 0.84 | SPHK1 (0.62) | SPHK1SPHK2CTSKS1PR4S1PR1 | |
| SCHEMBL13181089 | 0.81 | HPGD (0.57) | SPHK1THRATHRBS1PR1 | |
| SCHEMBL21049585 | 0.80 | SPHK1 (0.59) | SPHK1SPHK2THRATHRBS1PR1 | |
| SCHEMBL1314104 | 0.80 | PPARA (0.52) | CTSK | |
| SCHEMBL15014088 | 0.77 | NPC1 (0.62) | SPHK1THRATHRB | |
| SCHEMBL23007748 | 0.76 | SPHK1 (0.76) | SPHK1SPHK2S1PR4S1PR1S1PR3 | |
| SCHEMBL5454624 | 0.76 | CTSK (0.55) | CTSKS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230114304-A1 | DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-13 | — | — | US | disclosed |
| WO-2021030703-A1 | DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230114304-A1 | DEPALMITOYLATING COMPOSITIONS AND THE USE THEREOF | LIPA, LCAT, SGMS2 | SPHK1 492/4885SPHK2 510/4885THRA 4776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.