SCHEMBL23007992

SCHEMBL23007992

CCCC(=O)N(C=O)OCOC

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14535262 0.80 ALDH1A1 (0.36) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL22919637 0.75 TSHR (0.40) ALDH1A1CES2CES1
SCHEMBL21541035 0.75 ALDH1A1 (0.34) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL13636953 0.73 ALDH1A1 (0.34) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL19882382 0.72 ALDH1A1 (0.41) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL22621253 0.72 TSHR (0.38) ALDH1A1HDAC3HDAC1HDAC2HDAC8
SCHEMBL21011837 0.71 TSHR (0.45) ALDH1A1
SCHEMBL24982752 0.70 GAPDH (0.31) ALDH1A1CES2CES1
SCHEMBL22043673 0.69 ALDH1A1 (0.30) ALDH1A1
SCHEMBL19003436 0.69 NPSR1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778705-A1 DEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE NOF Corporation (JP) 2021-02-17 EP disclosed